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- 1From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedAdjuvant hormonal therapy for non-metastatic hormone receptor (HR)-positive breast cancer decreases risk of breast cancer recurrence and increases survival. However, some women do not initiate this life-saving...
- 2From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedThe aim of this analysis was to investigate the usefulness of Ki-67 labeling index (LI) for the identification of different prognostic subgroups in primary node-negative, triple negative breast cancer (TNBC) patients....
- 3From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedMolecular classification of breast cancer (BC) identified diverse subgroups that encompass distinct biological behavior and clinical implications, in particular in relation to prognosis, spread, and incidence of...
- 4From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedThe mutation pattern of breast cancer molecular subtypes is incompletely understood. The purpose of this study was to identify mutations in genes that may be targeted with currently available investigational drugs in...
- 5From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedProlactin (PRL) promotes the proliferation and survival of breast cancer cells in part via the transactivation of human epidermal growth factor receptor 2 (HER2), also known as Neu in rodents. A PRL receptor (PRLR)...
- 6From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedThe HER3 protein contributes to malignant transformation in breast and other cancer types as a consequence of elevated levels of expression, particularly in the presence of the HER2 protein. We show here that an...
- 7From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedErratum to: Breast Cancer Res Treat Author would like to amend the following corrections in the below Tables 3 and 4 which has been published unnoticed in the original version. Where, the article included an...
- 8From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedEstrogen signaling is a critical pathway that plays a key role in the pathogenesis of breast cancer. In a previous transcriptional profiling study, we identified a novel panel of estrogen-induced genes in breast cancer....
- 9From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedDocetaxel is a major drug in metastatic breast cancer (MBC) treatment. At progression, rechallenge with docetaxel can be discussed, according to previous efficacy and tolerance, as long as it was stopped for reasons...
- 10From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedIn addition to their major interest in refining disease classifications and improving diagnostic and prognostic accuracy by means of molecular signatures, microarrays have been proposed in breast cancer as an...
- 11From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedRecently, the number of studies on male breast cancer (MBC) has been increasing. However, as MBC is a rare disease there are difficulties to undertake studies to identify specific MBC subgroups. At present, it is still...
- 12From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedTo evaluate if biologically effective dose (BED), and in particular the duration of radiation treatment, has an effect on local relapse risk. Between January 2000 and December 2008 a total of 762 patients with T1-2 N0/+...
- 13From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedThe genetic component of breast cancer pre-disposition remains largely unexplained. Candidate gene case-control resequencing has identified predisposition genes characterised by rare, protein truncating mutations that...
- 14From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedThe goal of the present study was to evaluate the role of the tyrosine kinase receptor fibroblast growth factor-1 (FGFR1) and its ligand, the fibroblast growth factor 2 (FGF2) in determining the response to...
- 15From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedTriple-negative breast cancers are characterized by the triple-negative (ER/PgR/Her2 negative) phenotype, are frequently associated with BRCA gene mutation, and are not candidate to currently available endocrine and...
- 16From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedIn spite the close association of the triple-negative breast cancer immunophenotype with hereditary breast cancers and the BRCA1 pathway, there is a lack of population studies that determine the frequency of BRCA1...
- 17From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedUnambiguous classification of BRCAI and BRCA2 variants of uncertain significance (VUS) is a challenging task that vexes health care providers and has profound implications for patients and their family members. Numerous...
- 18From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedPsoriasin (S100A7), originally identified in psoriasis, is a calcium-binding protein belonging to the multigenic S100 family. In high-grade ductal carcinoma in situ, psoriasin was identified as one of the most abundant...
- 19From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedMetastases are the major cause of cancer-related deaths, but the mechanisms of the metastatic process remain poorly understood. In recent years, the involvement of microRNAs (miRNAs) in cancer has become apparent, and...
- 20From: Breast Cancer Research and Treatment. (Vol. 134, Issue 1) Peer-ReviewedTo investigate the effect of aromatase inhibitors (AI) on intestinal calcium absorption, measured using the gold-standard dual stable calcium isotope method. In this pilot study, we recruited 10 postmenopausal women...