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- Search Terms:ISSN: 14657392AndISSN: 14764679AndVolume Number: 13AndIssue Number: 5AndStart Page: 623AndDate: 2011 Revise Search
- 1From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedThis issue presents a series of specially commissioned articles that highlight exciting facets of stem cell research, including recent insights into the nature of pluripotency and how studying stem cells can increase our...
- 2From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedIn the hundred years since the creation of International Women's Day, great strides have been made in gender equality, but recent analysis suggests the need for further changes to enhance the progression of women in...
- 3From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedDuring metastatic cancer, cancerous cells spread into surrounding tissue or around the body. To do this, the cells use proteases to break through the extracellular matrix (ECM), but the molecular mechanisms that trigger...
- 4From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedThe exocyst complex tethers vesicles at sites of fusion through interactions with small GTPases. The G protein RalA resides on Glut4 vesicles, and binds to the exocyst after activation by insulin, but must then...
- 5From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedCiliates and flagellates temporarily swim backwards on collision by generating a mechanoreceptor potential. Although this potential has been shown to be associated with cilia in Paramecium, the molecular entity of the...
- 6From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedCOPII-coated vesicles drive protein export from the endoplasmic reticulum (ER), although the regulation of this event, both spatially and kinetically, remains unclear. TFG is now defined as a factor that modulates...
- 7From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedCOPI (coat protein I) and the clathrin-AP-2 (adaptor protein 2) complex are well-characterized coat proteins, but a component that is common to these two coats has not been identified. The GTPase-activating protein...
- 8From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedmDia3, a Diaphanous-related formin, localizes to kinetochores and is involved in metaphase chromosome alignment, but exactly how mDia3 regulates this process is unclear. Cheng et al. now report that mDia3 directly binds...
- 9From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedExport of proteins from the endoplasmic reticulum in COPII-coated vesicles occurs at defined sites that contain the scaffolding protein Sec16. We identify TFG-1, a new conserved regulator of protein secretion that...
- 10From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedHow APC/C-Cdc20 changes its substrate specificity in mitosis Daisuke Izawa and Jonathon Pines Nat. Cell Biol. 13, 223-233 (2011); published online 20 February 2011; corrected after print 31 March 2011 In the...
- 11From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedPluripotency and self-renewal are the hallmarks of embryonic stem cells. This state is maintained by a network of transcription factors and is influenced by specific signalling pathways. Current evidence indicates that...
- 12From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedJ. M. Mitchison FRS, known to most as Murdoch, Professor of Zoology at the University of Edinburgh from 1963 to 1988, died in Edinburgh on 17 March 2011 aged 88 years. Murdoch was a scientist who marched to the beat of...
- 13From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedOver the past decade, it has become increasingly clear that many tissues have regenerative capabilities. The challenge has been to find the stem cells or progenitors that are responsible for tissue renewal and repair....
- 14From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedInduced pluripotent stem (iPS) cells offer the possibility to generate patient-specific cell types for use in regenerative medicine. However, a long-lasting question remains: are iPS and embryonic stem cells equivalent?...
- 15From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedA plethora of cellular processes, including apoptosis, depend on regulated changes in mitochondrial shape and ultrastructure. The role of mitochondria and of their morphology during autophagy, a bulk degradation and...
- 16From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedConstitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation Maria Maldonado and Tarun M. Kapoor Nat. Cell Biol. 13, 475-482 (2011); published online 13 March 2011;...
- 17From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedThe discovery of methods to convert somatic cells into induced pluripotent stem cells (iPSCs) through expression of a small combination of transcription factors has raised the possibility of producing custom-tailored...
- 18From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedCyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is increasingly implicated in various neurodegenerative diseases. Deregulated Cdk5 activity has been associated with neuronal death, but the underlying...
- 19From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedStarvation of animals or cells triggers autophagic degradation of cell contents to retrieve nutrients, but, paradoxically, mitochondria enlarge. This is now shown to result from inhibition of mitochondrial fission...
- 20From: Nature Cell Biology. (Vol. 13, Issue 5) Peer-ReviewedThe circadian clock controls many metabolic, developmental and physiological processes in a time-of-day-specific manner in both plants and animals (1,2). The photoreceptors involved in the perception of light and...