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- Search Terms:ISSN: 14657392AndISSN: 14764679AndVolume Number: 13AndIssue Number: 4AndStart Page: 383AndDate: 2011 Revise Search
- 1From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedPlants reach for the sun by avoiding the shade and by directly growing towards the light. Two studies now suggest that the polar relocation of PIN3, a transporter directing the flow of the plant hormone auxin, drives...
- 2From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedPhototropism is an adaptation response, through which plants grow towards the light (1). It involves light perception and asymmetric distribution of the plant hormone auxin (2-12). Here we identify a crucial part of the...
- 3From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedCilia dysfunction has long been associated with cyst formation and ciliopathies (1). More recently, misoriented cell division has been observed in cystic kidneys (2), but the molecular mechanism leading to this...
- 4From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedCentrosomes are tethered to the nuclear envelope during the cell cycle, possibly to facilitate the coordination of spindle assembly and nuclear envelope breakdown in mitosis. Doye and colleagues now identify a...
- 5From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedThe contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143...
- 6From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedAutophagy is induced in response to stress and allows cells to survive through recycling of cellular components. As such, autophagy enables cancer cell survival in oxygen-poor tumour regions. White and colleagues now...
- 7From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedActivation of G-protein-coupled receptors (GPCRs) mobilizes compartmentalized pulses of cyclic AMP. The main cellular effector of cAMP is protein kinase A (PKA), which is assembled as an inactive holoenzyme consisting...
- 8From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedUnder nutrient-rich conditions, the nutrient-sensitive kinase mTOR (mammalian target of rapamycin) is recruited to the surface of lysosomes where it becomes activated and can promote cell growth and inhibit autophagy....
- 9From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedRegulation of microtubule dynamics at the cell cortex is important for cell motility, morphogenesis and division. Here we show that the Drosophila katanin Dm-Kat60 functions to generate a dynamic cortical-microtubule...
- 10From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedIn plant cells, organelle DNA replication (ODR) is coordinated with nuclear DNA replication (NDR), with ODR preceding NDR during cell cycle progression. We previously showed that the occurrence of ODR is signalled by a...
- 11From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedTwo papers in this issue show that dynein-binding proteins may regulate the G1-S transition through an effect on cilia. Ndel, a known partner of dynein light chain LC8, controls ciliary length in vitro and in zebrafish,...
- 12From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedFollowing DNA damage, cells protect their genomic integrity by initiating repair or apoptosis. Central to these responses is the Ataxia telangiectasia mutated (ATM) kinase, which is activated by double-strand breaks...
- 13From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedHIV (human immunodeficiency virus) diverts the cellular ESCRT (endosomal sorting complex required for transport) machinery to promote virion release from infected cells. The ESCRT consists of four heteromeric complexes...
- 14From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedEpithelial cell migration requires coordination of two actin modules at the leading edge: one in the lamellipodium and one in the lamella. How the two modules connect mechanistically to regulate directed edge motion is...
- 15From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedThe primary cilium is an antenna-like organelle that is dynamically regulated during the cell cycle. Ciliogenesis is initiated as cells enter quiescence, whereas resorption of the cilium precedes mitosis. The mechanisms...
- 16From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedFeng Liu, Su Wu, Hongwei Ren, Jun Gu Nat. Cell Biol. 13, 254-262 (2011); published online 20 February 2011; corrected after print 16 March 2011 In the version of this article initially published online and in...
- 17From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedIn February this year, the US House of Representatives passed a continuing resolution to reduce government spending in the 2011 fiscal year. As a consequence, the National Institutes of Health (NIH) budget for the...
- 18From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedThe ESCRT (endosomal sorting complex required for transport) complexes and associated proteins mediate membrane scission reactions, such as multivesicular body formation, the terminal stages of cytokinesis and...
- 19From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedDynamic adhesion of cells to their surrounding matrix is essential for cell migration during processes such as developmental morphogenesis, and is subverted in disease states, such as invasive cancer. In cells migrating...
- 20From: Nature Cell Biology. (Vol. 13, Issue 4) Peer-ReviewedmTOR (mammalian target of rapamycin) signalling and macroautophagy (henceforth autophagy) regulate numerous pathological and physiological processes, including cellular responses to altered nutrient levels. However, the...