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- Search Terms:ISSN: 14655411AndISSN: 1465542XAndVolume Number: 13AndIssue Number: 2AndStart Page: R42AndDate: 2011 Revise Search
- 1From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): M Izquierdo Sanz1 , F Tresserra Casas1 , G Nacho Rodríguez1 , R Fabregas Xaurado1 , M Cusido Gimferrer1 , C Ara Perez1 and S Baulies Caballero1 The aim was to compare the clinical features and prognosis of...
- 2From: Breast Cancer Research. (Vol. 13, Issue 2) Peer-ReviewedIntroduction Indole-3-carbinol (I3C), an autolysis product of glucosinolates present in cruciferous vegetables, and its dimeric derivative (3,3'-DIM) have been indicated as promising agents in preventing the...
- 3From: Breast Cancer Research. (Vol. 13, Issue 2) Peer-Reviewed
Nanomedicine: making controllable magnetic drug delivery possible for the treatment of breast cancer
A recent study published in Nano Letters documents the synthesis and performance of porous silica nanocapsules filled with magnetic nanoparticles as a controllable magnetic drug delivery vector. Under a remotely applied... - 4From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): R Plummer1 Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear DNA-binding enzyme activated by DNA strand breaks and has a key role in the signalling of DNA single-strand breaks as part of the repair...
- 5From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): KH Gravgaard1 , MB Lyng1 , A-V Laenkholm2 , R Sakilde3 , BS Nielsen3,4 , T Litman3 and HJ Ditzel1,5 Metastases are the major cause of cancer-related deaths, but the mechanisms of the metastatic process...
- 6From: Breast Cancer Research. (Vol. 13, Issue 2) Peer-ReviewedEstrogen receptor [alpha] (ER) is a major driver of breast cancer and the target of endocrine therapy. Full disclosure of the cofactors regulating ER interactions with chromatin and its transcriptional regulatory...
- 7From: Breast Cancer Research. (Vol. 13, Issue 2) Peer-ReviewedIntroduction The female sex steroids estrogen and progesterone are important in breast cancer etiology. It therefore seems plausible that variation in genes involved in metabolism of these hormones may affect breast...
- 8From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): EP Winer1 Trastuzumab has altered the natural history of HER2+ breast cancer. In the metastatic setting, it has improved progression-free and overall survival. In patients with operable breast cancer,...
- 9From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): A Gámez-Pozo1 , I Sánchez-Navarro1 , CA Castaneda2 , NI Ferrer3 , G de Velasco2 , FG Martínez3 , E Ciruelos2 and JÃ Fresno Vara1 microRNAs (miRNAs) constitute a new class of small noncoding RNAs that...
- 10From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): G Kharaishvili1 , D Simkova1 , M Cizkova2 , K Bouchalova2 , G Mgebrishvili1 , Z Kolar1 and J Bouchal1 We have shown that nestin expression is higher in breast carcinoma with a basal phenotype [1] and...
- 11From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): E Vega1 , E Ciruelos1 , N Valdiviezo1 , C Mendiola1 , L Manso1 , I Ghanem1 , M Dorta1 , T Pascual1 , C Flores2 and H Cortés-Funes1 Invasive lobular carcinoma (ILC) is the second most common type of...
- 12From: Breast Cancer Research. (Vol. 13, Issue 2) Peer-ReviewedStress exposure has been proposed to contribute to the etiology of breast cancer. However, the validity of this assertion and the possible mechanisms involved are not well established. Epidemiologic studies differ in...
- 13From: Breast Cancer Research. (Vol. 13, Issue 2) Peer-ReviewedIntroduction We have previously demonstrated that endoxifen is the most important tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen...
- 14From: Breast Cancer Research. (Vol. 13, Issue 2) Peer-ReviewedThe advent of genomic profiling technology has brought about revolutionary changes in our understanding of breast cancer metastasis. Gene expression analyses of primary tumors have been used to predict metastatic...
- 15From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): M Dowsett1 Luminal breast cancer constitutes almost all ER-positive tumours and as such constitutes around 75 to 80% of the disease. The luminal group is highly heterogeneous in terms of genetic...
- 16From: Breast Cancer Research. (Vol. 13, Issue 2) Peer-ReviewedIntroduction The adhesion protein junctional adhesion molecule-A (JAM-A) regulates epithelial cell morphology and migration, and its over-expression has recently been linked with increased risk of metastasis in...
- 17From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): R Trojanec1 , V Koudelakova1 , K Bouchalova1 , L Radova1 , H Ondryasova1 , E Krejci2 , M Megova1 , M Cizkova1,2 , S Mlcochova1 , B Melichar2 and M Hajduch1 In breast cancer (BC), several cytogenetic...
- 18From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): L Manso1 , E Ciruelos1 , M Codes2 , J De la Haba3 , A Galan4 , J Baena5 , A Jaen6 , M Gil7 , A Murias8 , I Blancas9 , E Gonzalez10 , D Perez11 , JL Bayo12 , J Mel13 , E Garcia-Martinez14 , R Cubedo15 and J...
- 19From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): S Loi1 Luminal (or clinically defined as estrogen receptor (ER)-positive and Her2-negative) breast cancer has long been successfully treated with anti-estrogen therapy, the first targeted anti-cancer agent...
- 20From: Breast Cancer Research. (Vol. 13, Issue Suppl 2) Peer-ReviewedAuthor(s): CL Arteaga1 The phosphatidylinositol-3 kinase (PI3K) pathway is overall the most frequently mutated pathway in cancer, with mutation and/or amplification of the genes encoding the PI3K catalytic subunits...