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- Search Terms:ISSN: 14786354AndISSN: 14786362AndVolume Number: 13AndIssue Number: 1AndStart Page: 202AndDate: 2011 Revise Search
- 1From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction Hand osteoarthritis (OA) is associated with pain, reduced grip strength, loss of range of motion and joint stiffness leading to impaired hand function and difficulty with daily activities. The...
- 2From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction In this study, we sought to determine the diagnostic value and clinical laboratory associations of autoantibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in...
- 3From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction In a murine model, interleukin (IL)-17 plays a critical role in the pathogenesis of arthritis. There are controversies, however, regarding whether IL-17 is a proinflammatory mediator in rheumatoid...
- 4From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction The aim of the present study was to compare bone mineral density (BMD) and body composition (BC) measurements as well as identify risk factors for low BMD and osteoporotic fractures in postmenopausal...
- 5From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction Transforming growth factor beta (TGF[beta]) plays a central role in morphogenesis, growth, and cell differentiation. This cytokine is particularly important in cartilage where it regulates cell...
- 6From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction The aim of this study was to examine the effect of blocking Toll-like receptor 2 (TLR2) in rheumatoid arthritis (RA) synovial cells. Methods RA synovial tissue biopsies, obtained under direct...
- 7From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction Recent evidence suggests that intervertebral disc (IVD) cells derived from degenerative tissue are unable to respond to physiologically relevant mechanical stimuli in the 'normal' anabolic manner, but...
- 8From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction The objective of this study was to compare the clinical usefulness of the new anti-double-stranded DNA nucleosome-complexed enzyme-linked immunosorbent assay (Anti-dsDNA-NcX ELISA), which is based on...
- 9From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction Autoantibodies have a central role in systemic lupus erythematosus (SLE). The presence of autoantibodies preceding disease onset by years has been reported both in patients with SLE and in those with...
- 10From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction The aim of this study was to assess the feasibility of diagnosing early rheumatoid arthritis (RA) by measuring selected metabolic biomarkers. Methods We compared the metabolic profile of patients...
- 11From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction The long-term treatment of rheumatoid arthritis (RA) most often involves a sequence of different therapies. The response to therapy, disease progression and detailed knowledge of the role of different...
- 12From: Arthritis Research & Therapy. (Vol. 13, Issue 1) Peer-ReviewedIntroduction Systemic sclerosis (SSc) is characterized by fibrosis and microvascular abnormalities including dysregulated angiogenesis. Chemokines, in addition to their chemoattractant properties, have the ability to...