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- 1From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): RE English1 , A Di Battista2 , RF Adams1 , L Winter1 and JA Noble2 Neoadjuvant chemotherapy is used as the primary treatment for locally advanced breast cancer to reduce tumour size and protect against...
- 2From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): Correspondence: Author details: doi: 10.1186/bcr2969...
- 3From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): D Tzias1 , S George1 , L Wilkinson1 , R Mehta1 , C Lobo1 , A Hainsworth1 and A Sharma1 It is widely accepted that there is an association between mammographic density and breast cancer risk [1]. Various...
- 4From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): L Dong1 , Y Chen1 and AG Gale1 All UK breast screeners can voluntarily undertake the PERFORMS scheme, where they examine recent screening cases receiving immediate feedback. Once all individuals have...
- 5From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): ND Forester1 , P Burrows1 , A Jack2 and A-M Wason1 Lymphoma diagnosis conventionally requires nodal excision biopsy, to allow histological subclassification of tumours on samples with preserved tissue...
- 6From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): J Long1 , CE Richardson1 , J Barrett1 , C Deacon1 and P Matey1 Recent guidelines advise that mammography should only be offered to women between the ages of 35 and 39 if clinical examination raises concern...
- 7From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): D O'Leary1 and L Rainford1 A study of symptomatic breast units geographically spread over Ireland collected image quality, compression and radiation dose data from 18 mammography units; so how do these...
- 8From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): A Newland1 , M Dumba1 and S Flais1 Routine MRI in the assessment of lobular carcinoma, invasive ductal carcinoma in dense breasts, patients younger than 35 or radioclinical discordance at the time of...
- 9From: Breast Cancer Research. (Vol. 13, Issue 1) Peer-ReviewedThe steroid hormones, estrogens and progesterone are key drivers of postnatal breast development and are linked to breast carcinogenesis. Experiments in the mouse mammary gland have revealed that they rely on paracrine...
- 10From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): EK Hughes1 , L Nassar1 , A Lim1 , N Barrett1 , S Comitis1 , D Cunningham1 , S Flais1 , A Gupta1 , G Ralleigh1 , V Stewart1 , W Svensson1 , R Williamson1 , N Zaman1 and K Satchithananda1 The automated...
- 11From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): D O'Leary1 and L Rainford1 Efforts to reduce radiation dose should be linked to and limited by image quality and the radiation dose should only be lowered to levels compatible with image quality for...
- 12From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): ME Fletcher1 , N Sharma1 and BG Dall1 The Leeds breast service treats over 500 breast cancers a year. The general practitioners (GPs) have always had access via the one-stop breast clinic or direct access...
- 13From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): D O'Leary1 , A Teape2 , J Hammond2 and L Rainford1 Objective critique of mammographic image quality (IQ) is vital to assess efficacy of services provided by mammography units. The European Guidelines for...
- 14From: Breast Cancer Research. (Vol. 13, Issue 1) Peer-ReviewedMutations arise during cell division at a predictable rate. Besides DNA repair mechanisms, the existence of cellular hierarchies that originate with a stem cell serve to reduce the number of divisions necessary for...
- 15From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): D Tzias1 , S George1 , L Wilkinson1 and R Mehta1 The UK five-point classification for radiological assessment of mammograms and ultrasound scans broadly enables evaluation of cancer risk [1], but no...
- 16From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): JS Wambani1 , GK Korir2 , MN Shyanguya1 and IK Korir3 Breast cancer constitutes 21% of all cancer cases and ranks third according to cancer type in Kenya. Mammography therefore remains a powerful...
- 17From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): JM Schneider1 and A Leaver2 Ultrasound and fine needle aspiration cytology (FNAC) are used to provide presurgical axillary assessment in breast cancer, in line with NICE guidance. An N1 to N5 ultrasound...
- 18From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): MA Crotch-Harvey1 Occult breast carcinoma presenting with axillary lymphadenopathy is an uncommon but difficult clinical problem. The most appropriate diagnostic pathway, the prognosis and the best form of...
- 19From: Breast Cancer Research. (Vol. 13, Issue Suppl 1) Peer-ReviewedAuthor(s): A Romsauerova1 , J Dewar1 , D Brown1 and A Evans1 TARGIT-A is a recent prospective randomised multicentre controlled trial comparing intraoperative radiotherapy (IORT) and external beam whole breast...
- 20From: Breast Cancer Research. (Vol. 13, Issue 1) Peer-ReviewedIntroduction The purpose of the present study was to investigate the relationship of expression of hypoxia inducible factor (HIF)-1[alpha]-modifying enzymes prolyl hydroxylase (PHD)1, PHD2 and PHD3 to response of...