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- 1From: Trials. (Vol. 13) Peer-ReviewedAuthors: Peter AG Sandercock (corresponding author) [1]; Maciej Niewada [2,3]; Anna Cz?onkowska [2,3] Correction Following the publication of our article [1] we became aware of errors introduced in the following...
- 2From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Well-designed and properly executed randomized controlled trials (RCTs) provide the best evidence on the efficacy of healthcare interventions. Mental health has a strong tradition of using trial to...
- 3From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground In the last few years, excessive internet use and computer gaming have increased dramatically. Salience, mood modification, tolerance, withdrawal symptoms, conflict, and relapse have been defined as...
- 4From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Exercise training (ET) in addition to optimal medical therapy (OMT) in patients with stable coronary artery disease (CAD) has been demonstrated to be superior to percutaneous coronary interventions (PCI)...
- 5From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Despite bronchiectasis being increasingly recognised as an important cause of chronic respiratory morbidity in both indigenous and non-indigenous settings globally, high quality evidence to inform...
- 6From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Many women try to stop smoking in pregnancy but fail. One difficulty is that there is insufficient evidence that medications for smoking cessation are effective and safe in pregnancy and thus many women...
- 7From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground When planning a randomized controlled trial (RCT), investigators must select randomization and allocation procedures based upon a variety of factors. While third party randomization is cited as being among...
- 8From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Enrollment in interventional therapeutic clinical trials is a small fraction of all patients who might participate given reasonable access. Methods A hierarchical approach is utilized in measuring...
- 9From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Extended smoking cessation follow-up after hospital discharge significantly increases abstinence. Hospital smoke-free policies create a period of 'forced abstinence' for smokers, thus providing an...
- 10From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground The end of life for cancer patients is the ultimate stage of the disease, and care in this setting is important as it can improve the wellbeing not only of patients, but also the patients' family and close...
- 11From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Many people with dementia experience anxiety, which can lead to decreased independence, relationship difficulties and increased admittance to care homes. Anxiety is often treated with antipsychotic...
- 12From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Multi-element interventions for first-episode psychosis (FEP) are promising, but have mostly been conducted in non-epidemiologically representative samples, thereby raising the risk of underestimating the...
- 13From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Modern clinical-research practice favors placebo controls over usual-care controls whenever a credible placebo exists. An unrecognized consequence of this preference is that clinicians are more limited in...
- 14From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground There is compelling evidence that psychological factors may have the same or even greater impact on the possibility of adverse events on cardiac diseases (CD) than other traditional clinical risk factors....
- 15From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Despite declines over recent years, youth tobacco and other substance use rates remain high. Latino youth are at equal or increased risk for lifetime tobacco, alcohol, marijuana, and other illicit drug use...
- 16From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground IVF is a costly treatment option for women, their partners, and the public. Therefore new therapies that improve reproductive and health outcomes are highly desirable. There is a growing body of research...
- 17From: Trials. (Vol. 13) Peer-ReviewedBackground Central sensitization has recently been documented in patients with knee osteoarthritis (OAk). So far, the presence of central sensitization has not been considered as a confounding factor in studies...
- 18From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Intracranial hemorrhage occurs in over 60% of severe head injuries in one of three types: extradural (EDH); subdural (SDH); and intraparenchymal (TICH). Prompt surgical removal of significant SDH and EDH...
- 19From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Postoperative surgical site infections cause substantial morbidity, prolonged hospitalization, costs and even mortality and remain one of the most frequent surgical complications. Approximately 14% to 30%...
- 20From: Trials. (Vol. 13, Issue 1) Peer-ReviewedBackground Many postnatal women are insufficiently physically active in the year after childbirth and could benefit from interventions to increase activity levels. However, there is limited information about the...