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- 1From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedRapamycin and its analogues inhibit mTOR, which leads to decreased protein synthesis and decreased cancer cell proliferation in many experimental systems. Adenosine 5'-monophosphate-activated protein kinase (AMPK)...
- 2From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedFine needle aspiration cytology (FNAC) and core needle biopsy (CNB) are widely used in diagnosing breast lesions, with both achieving high sensitivity and specificity. Whether FNAC or CNB is better remains highly...
- 3From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedIt is not known whether the HER2 status of malignant CSF cells coincides with that of the original breast carcinoma cells. We investigated whether CSF cytology specimens were suitable to evaluate HER2 status by...
- 4From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedThe last decade has seen improvement in survival for women with breast cancer and increased recognition that many survivors have long-term sequelae due to cancer and/ or its treatments. Concerns expressed by breast...
- 5From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedIrreversible electroporation (IRE) is a therapeutic technology for the ablation of soft tissues using electrodes to deliver intense but short electric pulses across a cell membrane, creating nanopores that lead to cell...
- 6From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedGli1 is a transcription factor and oncogene with documented roles in the progression of several cancer types, including cancers of the skin and pancreas. The contribution of Gli1 to the progression of breast cancer is...
- 7From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedZinc-finger enhancer binding protein (ZEB1) is a transcription factor involved in the progression of cancer primarily through promoting epithelial to mesenchymal transition (EMT). ZEB1 represses the expression of...
- 8From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedThis study investigated the trends over time in age and stage specific population-based survival of estrogen receptor negative (ER-) breast cancer patients by examining the fraction of cured patients and the median...
- 9From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedThe aim of this study was to examine TOP2A gene copy number changes as a means to identify groups of breast cancer patients with superior benefit from treatment with anthracyclines. Tumour tissue was retrospectively...
- 10From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedBy comparison of mass spectra from a small cohort of nipple aspiration fluids (NAF), we previously discovered a panel of five candidate breast cancer biomarkers among them an unidentified 4.7 kD peptide BF5. The...
- 11From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedTo undertake a systematic review of three first-line treatments (letrozole, anastrozole and exemestane) for hormone sensitive advanced or metastatic breast cancer (MBC) in post-menopausal women. We searched six...
- 12From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedSeveral common single-nucleotide polymorphisms (SNPs) within the XRCC2 gene have been identified as potential breast cancer susceptibility loci and a coding SNP in exon 3 (Arg188His, rs3218536) has been extensively...
- 13From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedWe analyzed breast cancer subtypes using Korean Breast Cancer Society Registration Program data to compare clinical features and prognosis for triple-negative breast cancer (TNBC). A cohort of 26,767 breast cancer...
- 14From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedGPR30 is a novel G protein-coupled estrogen receptor (ER) associated with metastases in breast cancer (BC) and poor survival in endometrial and ovarian tumors. The association of GPR30 expression with inflammatory...
- 15From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedThe Catechol-O-methyltransferase (COMT) plays an important role in the development of breast cancer. Many previous epidemiologic studies explored the association of COMT Val158Met polymorphism with breast cancer...
- 16From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedAxillary lymph node status is the most powerful prognostic indicator in patients with breast cancer. FDG-PET has been suggested as a non-invasive method of staging the axilla. The aim of this study was to review and...
- 17From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedIn a series of recent studies, in addition to CD44 and CD24 expression, ALDH1 has been described to play a crucial role in identification of putative cancer stem cells (CSCs) and/or potential cancer initiating cells in...
- 18From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedRecent reports have shown the involvement of tumor burden as well as GM-CSF in supporting myeloid-derived suppressor cells (MDSC). However, it is not known what progenitor cells may differentiate into MDSC...
- 19From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedStudies on polymorphisms of Xeroderma Pigmentosum Group D Protein (XPD) and breast cancer risk are inconclusive. To elucidate the role of XPD genotypes, all available studies were considered in this meta-analysis. The...
- 20From: Breast Cancer Research and Treatment. (Vol. 123, Issue 1) Peer-ReviewedIt has been over 100 year since Beatson demonstrated the benefit of oophoretcomy for the management of advanced breast cancer [1], and over 60 years since the first randomized trial of ovarian ablation in premenopausal...