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- 1From: Genes and Immunity. (Vol. 12, Issue 4) Peer-ReviewedA common allele at the TAGAP gene locus demonstrates a suggestive, but not conclusive association with risk of rheumatoid arthritis (RA). To fine map the locus, we conducted comprehensive imputation of CEU HapMap...
- 2From: Genes and Immunity. (Vol. 12, Issue 4) Peer-ReviewedInfection of inbred mouse strains with Citrobacter rodentium represents an ideal model to reveal the genetic factors controlling host resistance to noninvasive enteric bacterial pathogens. We have chosen a positional...
- 3From: Genes and Immunity. (Vol. 12, Issue 4) Peer-ReviewedChronic hepatitis C virus (HCV) infection patients exhibit different sustained virological responses (SVRs) following the treatment with pegylated interferon-[alpha] (IFN-[alpha]) and ribavirin. Genome-wide association...
- 4From: Genes and Immunity. (Vol. 12, Issue 4) Peer-ReviewedMortality of pups at 8-12 weeks of age was frequently observed in Frisian Water Dogs. Blood parameters and clinical signs of newborns from three litters were monitored. Three pups from two litters showed strongly...
- 5From: Genes and Immunity. (Vol. 12, Issue 4) Peer-ReviewedLupus susceptibility loci on chromosome 1 have an important role in the development of autoimmunity in the New Zealand Black (NZB) mouse. We have previously shown that C57BL/6 congenic mice with an introgressed...
- 6From: Genes and Immunity. (Vol. 12, Issue 4) Peer-ReviewedMPYS, also known as STING and MITA, is an interferon (IFN)[beta] stimulator essential for host defense against RNA, DNA viruses and intracellular bacteria. MPYS also facilitates the adjuvant activity of DNA vaccines....
- 7From: Genes and Immunity. (Vol. 12, Issue 4) Peer-ReviewedSystemic lupus erythematosus (SLE) is a prototypic autoimmune disorder with a complex pathogenesis in which genetic, hormonal and environmental factors have a role. Rare mutations in the TREX1 gene, the major mammalian...
- 8From: Genes and Immunity. (Vol. 12, Issue 4) Peer-ReviewedThe major histocompatibility complex class II (MHC-II) locus encodes a cluster of highly polymorphic genes HLA-DR, -DQ and -DP that are co-expressed in mature B lymphocytes. Two cell lines were established over 30 years...
- 9From: Genes and Immunity. (Vol. 12, Issue 4) Peer-ReviewedLymphocytes and myeloid cells (monocyte/macrophages) have important roles in multiple types of diseases characterized by unresolved inflammation. The relatively recent appreciation of obesity, insulin resistance and...
- 10From: Genes and Immunity. (Vol. 12, Issue 4) Peer-ReviewedCorrection to: Genes and Immunity (2010) 11, 490-496; doi:10.1038/gene.2010.17 The following errors are noted: (1) Affiliation 1 was incorrect; the correct affiliations are shown above. (2) Page 491, column 2,...