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- Search Terms:ISSN: 14655411AndISSN: 1465542XAndVolume Number: 12AndIssue Number: 2AndStart Page: 104AndDate: 2010 Revise Search
- 1From: Breast Cancer Research. (Vol. 12, Issue 2) Peer-ReviewedIdentification and characterization of cancer-initiating cells (CICs) enriched for stem cell-like functions and the establishment of a link between CICs and tumor recurrence, chemotherapy resistance and radiation...
- 2From: Breast Cancer Research. (Vol. 12, Issue 2) Peer-ReviewedThere is a strong association between BRCA1 mutation carrier status and estrogen receptor-negative breast cancer. This has led to the idea that estrogen receptor-positive breast cancers in BRCA1 mutation carriers may be...
- 3From: Breast Cancer Research. (Vol. 12, Issue Suppl 2) Peer-ReviewedAlthough the introduction of novel therapies and drug combinations has improved the prognosis of metastatic breast cancer, the disease remains incurable. Increased knowledge of the biology and the molecular alterations...
- 4From: Breast Cancer Research. (Vol. 12, Issue 2) Peer-ReviewedTwo recent studies show that epigenetics and inflammation play a relevant role in the regulation of transformation and cancer cell self-renewal in breast tumours, opening up the possibility that cancer progression can...
- 5From: Breast Cancer Research. (Vol. 12, Issue 2) Peer-ReviewedAccumulating evidence suggests that many cancers, including BRCA1- and BRCA2-associated breast cancers, are deficient in DNA repair processes. Both hereditary and sporadic breast cancers have been found to have...
- 6From: Breast Cancer Research. (Vol. 12, Issue 2) Peer-ReviewedThe protein serine/threonine kinase Akt, also known as protein kinase B (PKB), is arguably the most important signalling nexus in the cell. Akt integrates a plethora of extracellular signals to generate diverse...
- 7From: Breast Cancer Research. (Vol. 12, Issue Suppl 2) Peer-ReviewedPerou's molecular classification defines tumors that neither express hormone receptors nor overexpress HER2 as triple-negative (TN) tumors. These tumors account for approximately 15% of breast cancers. The so-called...
- 8From: Breast Cancer Research. (Vol. 12, Issue 2) Peer-ReviewedMicroRNAs (miRNAs) are a major class of small endogenous RNA molecules that post-transcriptionally inhibit gene expression. Many miRNAs have been implicated in several human cancers, including breast cancer. Here we...
- 9From: Breast Cancer Research. (Vol. 12, Issue 2) Peer-ReviewedAuthor(s): Gordon C Wishart1,7 , Elizabeth M Azzato2,3 , David C Greenberg4 , Jem Rashbass4 , Olive Kearins5 , Gill Lawrence5 , Carlos Caldas1,6,7 and Paul DP Pharoah2 Following the publication of our article [1] we...
- 10From: Breast Cancer Research. (Vol. 12, Issue 2) Peer-ReviewedMetastasis remains the leading cause of death among cancer patients because few effective treatment options are available. A recent paper proposes a new twist on metastasis. The paper shows that circulating tumor cells...
- 11From: Breast Cancer Research. (Vol. 12, Issue Suppl 2) Peer-ReviewedResistance to chemotherapy is a major obstacle to the effective treatment of many tumor types. Although many anticancer therapies can alter tumor growth, in most cases the effect is not long lasting. Consequently, there...