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- 1From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedOlfactory systems utilize discrete neural pathways to process and integrate odorant information. In Drosophila, axons of first-order olfactory receptor neurons (ORNs) and dendrites of second-order projection neurons...
- 2From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedVisual attention can improve behavioral performance by allowing observers to focus on the important information in a complex scene. Attention also typically increases the firing rates of cortical sensory neurons. Rate...
- 3From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedPruning that selectively eliminates neuronal processes is crucial for the refinement of neural circuits during development. In Drosophila, the class IV dendritic arborization neuron (ddaC) undergoes pruning to remove...
- 4From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedThe cortex is sensitive to weak stimuli, but responds to stronger inputs without saturating. The mechanisms that enable this wide range of operation are not fully understood. We found that the amplitude of excitatory...
- 5From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedThe adult mouse subependymal zone (SEZ) harbors neural stem cells that are thought to exclusively generate GABAergic interneurons of the olfactory bulb. We examined the adult generation of glutamatergic juxtaglomerular...
- 6From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedIn addition to their role in the immune response, peptide ligands of major histocompatibility complex (MHC) molecules function as olfactory cues for subsets of vomeronasal sensory neurons (VSNs) in the mammalian nose....
- 7From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedThe firing of most hippocampal neurons is modulated by the theta rhythm, but it's not clear how and where the rhythm is generated. A study now shows that the required machinery for theta generation lies in local...
- 8From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedAdverse early life events can induce long-lasting changes in physiology and behavior. We found that early-life stress (ELS) in mice caused enduring hypersecretion of corticosterone and alterations in passive stress...
- 9From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedMotor cortex neurons are activated at different times during self-initiated voluntary movement. However, the manner in which excitatory and inhibitory neurons in distinct cortical layers help to organize voluntary...
- 10From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedThe pruning of unneeded axons and dendrites is crucial for circuitry maturation, but poorly understood on the molecular level. During Drosophila metamorphosis, the transcription factor Sox14 acts as a context-dependent...
- 11From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedA network of cortical brain regions, including the insula and anterior cingulate cortex (ACC), has been proposed as the critical and sole substrate for interoceptive awareness. Combining lesion and pharmacological...
- 12From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedHippocampal theta rhythm is crucial for spatial memory and is thought to be generated by extrinsic inputs. In contrast, using a complete rat hippocampus in vitro, we found several intrinsic, atropine-resistant theta...
- 13From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedAccumulating evidence has suggested that professional players of American football might be at increased risk of early-onset dementia. This October, a string of heated debates on this issue culminated in a US...
- 14From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-Reviewed
Experience-dependent compartmentalized dendritic plasticity in rat hippocampal CA1 pyramidal neurons
The excitability of individual dendritic branches is a plastic property of neurons. We found that experience in an enriched environment increased propagation of dendritic [Na.sup.+] spikes in a subset of individual... - 15From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedAxonal maturation and myelination are essential processes for establishing an efficient neuronal signaling network. We found that nardilysin (N-arginine dibasic convertase, also known as Nrd1 and NRDc), a...
- 16From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedDuring the development of peripheral ganglia, 50% of the neurons that are generated undergo apoptosis. How the massive numbers of corpses are removed is unknown. We found that satellite glial cell precursors are the...
- 17From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedWe sought to address the fundamental question of how stem cell microenvironments can regulate self-renewal. We found that Notch was active in astroglia-like neural stem cells (NSCs), but not in transit-amplifying...
- 18From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedAccumulation of cerebral amyloid-[beta] peptide (A[beta]) is essential for developing synaptic and cognitive deficits in Alzheimer's disease. However, the physiological functions of A[beta], as well as the primary...
- 19From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedThe vascular niche-derived factor PEDF enhances Notch signaling in adult neural stem cells via an unexpected mechanism involving nuclear export of a transcriptional repressor, to promote both proliferation and...
- 20From: Nature Neuroscience. (Vol. 12, Issue 12) Peer-ReviewedAm I Making Myself Clear? A Scientist's Guide to Talking to the Public By Cornelia Dean Harvard University Press, 2009 288 pages, hardcover, $19.95 ISBN 0674036352 In her new book, Am I Making Myself...