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- 1From: Microbial Cell Factories. (Vol. 12) Peer-ReviewedBackground Mannanase is an enzyme that can catalyze random hydrolysis of beta-1,4-mannosidic linkages in the main chain of mannans, glucomannans and galactomannans which are the key polymers in hemicellulose. It has...
- 2From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground The Gram-positive actinomycete Rhodococcus opacus is widely studied for its innate ability to store large amounts of carbon in the form of triacylglycerol (TAG). Several groups have demonstrated that R....
- 3From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Biotechnological production of the traditional petrochemical ethylene is presently being explored using yeasts as well as bacteria. In this study we quantify the specific ethylene production levels at...
- 4From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground To engineer Saccharomyces cerevisiae for efficient xylose utilization, a fungal pathway consisting of xylose reductase, xylitol dehydrogenase, and xylulose kinase is often introduced to the host strain....
- 5From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Monoterpenes are a class of natural C.sub.10 compounds with a range of potential applications including use as fuel additives, fragrances, and chemical feedstocks. Biosynthesis of monoterpenes in...
- 6From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Membrane protein research is frequently hampered by the low natural abundance of these proteins in cells and typically relies on recombinant gene expression. Different expression systems, like mammalian...
- 7From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Norleucine and norvaline belong to a group of non-canonical amino acids which are synthesized as byproducts in the branched chain amino acid metabolism of Escherichia coli. The earlier observed...
- 8From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground A large range of genetic tools has been developed for the optimal design and regulation of complex metabolic pathways in bacteria. However, fewer tools exist in yeast that can precisely tune the expression...
- 9From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground L-ascorbic acid (L-AA) is naturally synthesized in plants from D-glucose by 10 steps pathway. The pathway branch to synthesize L-galactose, the key intermediate for L-ascorbic acid biosynthesis, has been...
- 10From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Accumulation of inorganic polyphosphate (polyP), a persistent trait throughout the whole Tree of Life, is claimed to play a fundamental role in enduring environmental insults in a large variety of...
- 11From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Glycosaminoglycans, such as hyaluronic acid, heparin, and chondroitin sulfate, are among the top ranked products in industrial biotechnology for biomedical applications, with a growing world market of...
- 12From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Repressible promoters are a useful tool for down-regulating the expression of genes, especially those that affect cell viability, in order to study cell physiology. They are also popular in...
- 13From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground The bacterium Escherichia coli can be grown employing various carbohydrates as sole carbon and energy source. Among them, glucose affords the highest growth rate. This sugar is nowadays widely employed as...
- 14From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Moths (Lepidoptera) are highly dependent on chemical communication to find a mate. Compared to conventional unselective insecticides, synthetic pheromones have successfully served to lure male moths as a...
- 15From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Polylactic acid is a renewable raw material that is increasingly used in the manufacture of bioplastics, which offers a more sustainable alternative to materials derived from fossil resources. Both lactic...
- 16From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Biologically active inclusion bodies (IBs) have gained much attention in recent years. Fusion with IB-inducing partner has been shown to be an efficient strategy for generating active IBs. To make full use...
- 17From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Science-based recombinant bioprocess designs as well as the design of statistical experimental plans for process optimization (Design of Experiments, DoE) demand information on physiological bioprocess...
- 18From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Hepatitis C virus (HCV) is a common and leading cause for liver cirrhosis and hepatocellular carcinoma. Current therapies to treat HCV infection are shown to be partially effective and poorly tolerated....
- 19From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground Disulfide-rich proteins or DRPs are versatile bioactive compounds that encompass a wide variety of pharmacological, therapeutic, and/or biotechnological applications. Still, the production of DRPs in...
- 20From: Microbial Cell Factories. (Vol. 12, Issue 1) Peer-ReviewedBackground In vivo recombination of overlapping DNA fragments for assembly of large DNA constructs in the yeast Saccharomyces cerevisiae holds great potential for pathway engineering on a small laboratory scale as...