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- Search Terms:ISSN: 00219738AndISSN: 15588238AndVolume Number: 118AndIssue Number: 12AndStart Page: 4002AndDate: 2008 Revise Search
- 1From: Journal of Clinical Investigation. (Vol. 118, Issue 12) Peer-ReviewedNeurotoxic amyloid β peptide (Aβ) accumulates in the brains of individuals with Alzheimer disease (AD). The APOE4 allele is a major risk factor for sporadic AD and has been associated with increased brain parenchymal and...