Showing Results for
- Academic Journals (7)
Search Results
- 7
Academic Journals
- 7
- Search Terms:ISSN: 14655411AndISSN: 1465542XAndVolume Number: 11AndIssue Number: 6AndStart Page: R87AndDate: 2009 Revise Search
- 1From: Breast Cancer Research. (Vol. 11, Issue 6) Peer-ReviewedLoss of cell cycle control is a hallmark of cancer, and aberrations in the cyclin-CDK-RB (cyclin-dependent kinase-retinoblastoma protein) pathway are common in breast cancer. Consequently, inhibition of this pathway is...
- 2From: Breast Cancer Research. (Vol. 11, Issue 6) Peer-ReviewedIntroduction The invasive, mesenchymal phenotype of CD44.sup.posCD24.sup.neg breast cancer cells has made them a promising target for eliminating the metastatic capacity of primary tumors. It has been previously...
- 3From: Breast Cancer Research. (Vol. 11, Issue 6) Peer-ReviewedThe high rate of glucose utilization by cancer cells has been well characterized. Recent data suggest that when normal mammary epithelial cells are cultured under nonadherent conditions, glucose consumption decreases,...
- 4From: Breast Cancer Research. (Vol. 11, Issue 6) Peer-ReviewedPoly(ADP-ribose) polymerase (PARP) inhibitors have been explored as therapeutic agents for the treatment of hereditary breast and ovarian cancers harboring mutations in BRCA1 or BRCA2. In a new study, Inbar-Rozensal and...
- 5From: Breast Cancer Research. (Vol. 11, Issue 6) Peer-ReviewedThe phenotypic diversity of breast cancer has been proposed to result from different target cell types undergoing oncogenic transformation and giving rise to cancer stem cells. Global gene expression profiling revealed...
- 6From: Breast Cancer Research. (Vol. 11, Issue 6) Peer-ReviewedIntroduction Activator protein-2 (AP-2) [alpha] and AP-2[gamma] transcription factors contribute to ERBB2 gene overexpression in breast cancer. In order to understand the mechanism by which the ERBB2 gene is...
- 7From: Breast Cancer Research. (Vol. 11, Issue 6) Peer-ReviewedEpithelial-mesenchymal plasticity in breast carcinoma encompasses the phenotypic spectrum whereby epithelial carcinoma cells within a primary tumor acquire mesenchymal features and re-epithelialize to form a cohesive...