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- 1From: Critical Care. (Vol. 11) Peer-ReviewedAbstract Introduction Critical illness polyneuropathy (CIP) is a clinical condition frequently seen in patients being treated in critical care units in the final stage of sepsis. The etiopathology of CIP is still...
- 2From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction Decreases in oxygen saturation (SO.sub.2 ) and lactate concentration [Lac] from superior vena cava (SVC) to pulmonary artery have been reported. These gradients ([DELTA]SO.sub.2 and [DELTA][Lac]) are...
- 3From: Critical Care. (Vol. 11) Peer-ReviewedBackground Recombinant human activated protein C (rhAPC) has been reported to be cost-effective in severely ill septic patients in studies using data from a pivotal randomized trial. We evaluated the...
- 4From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction Many innovative cardiopulmonary bypass (CPB) systems have recently been proposed by the industry. With few differences, they all share a philosophy based on priming volume reduction, closed circuit with...
- 5From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction Several studies have shown that maximizing stroke volume (or increasing it until a plateau is reached) by volume loading during high-risk surgery may improve post-operative outcome. This goal could be...
- 6From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction Positive pressure ventilation with large tidal volumes has been shown to cause release of cytokines, including macrophage inflammatory protein-2 (MIP-2), a functional equivalent of human IL-8, and...
- 7From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other nonlactate, unmeasured anions...
- 8From: Critical Care. (Vol. 11) Peer-ReviewedBackground Trauma is a leading cause of mortality and morbidity, with traumatic brain injury (TBI) and uncontrolled hemorrhage responsible for the majority of these deaths. Recombinant activated factor VIIa (rFVIIa)...
- 9From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction Various cohort studies have shown that acute (short-term) mortality rates in unselected critically ill patients may have improved during the past 15 years. Whether these benefits also affect acute and...
- 10From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction The clinical and economic burden of ventilator-associated pneumonia (VAP) is uncontested. We conducted the present study to determine whether low nurse-to-patient ratio increases the risk for VAP and...
- 11From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction Protective ventilatory strategies have been applied to prevent ventilator-induced lung injury in patients with acute lung injury (ALI). However, adjustment of positive end-expiratory pressure (PEEP) to...
- 12From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction Prediction of death and prolonged mechanical ventilation is important in terms of projecting resource utilization and in establishing protocols for clinical studies of acute lung injury (ALI). We aimed...
- 13From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction We sought to determine and compare the effects of vasopressin, fluid resuscitation and saline placebo on haemodynamic variables and short-term survival in an abdominal vascular injury model with...
- 14From: Critical Care. (Vol. 11) Peer-ReviewedBackground The aim of the present study was to evaluate the C-reactive protein level, the body temperature and the white cell count in patients after prescription of antibiotics in order to describe the clinical...
- 15From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction The present study compared measurements of cardiac output by an arterial pressure-based cardiac output (APCO) analysis method with measurement by intermittent thermodilution cardiac output (ICO) via...
- 16From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction The objective of the present study was to compare postoperative cardiac troponin I (cTnI) release and the thresholds of cTnI that predict adverse outcome after elective coronary artery bypass graft...
- 17From: Critical Care. (Vol. 11) Peer-ReviewedAbstract Introduction Methadone, the most widely delivered maintenance therapy for heroin addicts, may be responsible for life-threatening poisonings with respiratory depression. The toxicokinetics and the...
- 18From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction Accurate and timely diagnosis of community-acquired bacterial infections in patients with systemic inflammation remains challenging both for clinician and laboratory. Combinations of markers, as opposed...
- 19From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction Recombinant human activated protein C (APC) therapy has been shown to reduce short-term mortality in patients with severe sepsis. However, survivors of sepsis may have long-term complications affecting...
- 20From: Critical Care. (Vol. 11) Peer-ReviewedIntroduction The relationship between oxygen delivery and consumption in sepsis is impaired, suggesting a microcirculatory perfusion defect. Recombinant human erythropoietin (rHuEPO) regulates erythropoiesis and also...