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- 1From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedIon channels are generally described by bedrock characteristics that include such parameters as ionic selectivity, conductance, voltage sensitivity, sensitization and inactivation, and pharmacological profiles, among...
- 2From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-Reviewed
Instantaneous correlation of excitation and inhibition during ongoing and sensory-evoked activities.
Temporal and quantitative relations between excitatory and inhibitory inputs in the cortex are central to its activity, yet they remain poorly understood. In particular, a controversy exists regarding the extent of... - 3From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedTransient receptor potential vanilloid 1 (TRPV1) is an ion channel that is gated by noxious heat, capsaicin and other diverse stimuli. It is a nonselective cation channel that prefers [Ca.sup.2+] over [Na.sup.+]. These...
- 4From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedTo the editor: Viswanathan and Freeman [1] claim that oxygen concentration and, by inference, blood oxygen level--dependent (BOLD) functional magnetic resonance imaging (fMRI) reflect synaptic activity more than...
- 5From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedEver wondered what is it about emotional or traumatic memories that make them more vivid, recurrent and stable than other memories? In this issue, Baumgartel et al. [1] show that calcineurin (a phosphatase also called...
- 6From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedNeuroscientists have made impressive progress in describing the anatomical wiring plans in neocortical and hippocampal modules, as well as the physiology of specific local circuit connections [1]. These brain regions,...
- 7From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedA saccadic eye movement causes a variety of transient perceptual sequelae that might be the results of corollary discharge. Here we describe the neural circuits for saccadic corollary discharge that modulates activity...
- 8From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedThere has been a long controversy as to whether subjectively 'free' decisions are determined by brain activity ahead of time. We found that the outcome of a decision can be encoded in brain activity of prefrontal and...
- 9From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedThe rod pigment, rhodopsin, shows spontaneous isomerization activity. This quantal noise produces a dark light of ~0.01 photons [s.sup.-1] [rod.sup.-1] in human, setting the threshold for rod vision. The spontaneous...
- 10From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedA young male zebra finch (Taeniopygia guttata) learns to sing by copying the vocalizations of an older tutor in a process that parallels human speech acquisition. Brain pathways that control song production are well...
- 11From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedYoung birds learn to sing during a critical period of development. Although the song system circuits have been identified, the molecular systems responsible for song template memorization have remained unknown. On page...
- 12From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedStudies of cortical connections or neuronal function in different cerebral areas support the hypothesis that parallel cortical processing streams, similar to those identified in visual cortex, may exist in the auditory...
- 13From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedDelineating neurons that underlie complex behaviors is of fundamental interest. Using adeno-associated virus 2, we expressed the Drosophila allatostatin receptor in somatostatin (Sst)-expressing neurons in the...
- 14From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedSynaptic dysfunction caused by oligomeric assemblies of amyloid-p peptide (AP) has been linked to cognitive deficits in Alzheimer's disease. Here we found that incubation of primary cortical neurons with oligomeric Aβ...
- 15From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedTen years ago this month, the Nature Neuroscience editors were obsessed with one question: How many manuscripts would he ready for the first issue? Asking the referees to return their reviews quickly had produced enough...
- 16From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-Reviewed
Theta phase--specific codes for two-dimensional position, trajectory and heading in the hippocampus.
Temporal coding is a means of representing information by the time, as opposed to the rate, at which neurons fire. Evidence of temporal coding in the hippocampus comes from place cells, whose spike times relative to... - 17From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedFor a lot of processing in the brain, two pathways are clearly better than one. In the visual system, two anatomically and functionally distinct pathways are thought to be specialized for processing information about...
- 18From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedEmotional memory is a rapidly acquired and persistent form of memory, and its robustness is in part determined by the initial strength of the memory. Here, we provide new evidence that the protein phosphatase calcineurin...
- 19From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedThe neural mechanisms underlying visual estimation of subsecond durations remain unknown, but perisaccadic underestimation of interflash intervals may provide a clue as to the nature of these mechanisms. Here we found...
- 20From: Nature Neuroscience. (Vol. 11, Issue 5) Peer-ReviewedNeural activity in the cerebral cortex can explain many aspects of sensory perception. Extensive psychophysical and neurophysiological studies of visual motion and vibrotactile processing show that the firing rate of...