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- 1From: Malaria Journal. (Vol. 11) Peer-ReviewedBackground The avian disease system in Hawaii offers an ideal opportunity to investigate host-pathogen interactions in a natural setting. Previous studies have recognized only a single mitochondrial lineage of avian...
- 2From: Malaria Journal. (Vol. 11) Peer-ReviewedBackground More than 75% of the total area of Ethiopia is malarious, making malaria the leading public health problem in Ethiopia. The aim of this study was to investigate the prevalence rate and the associated...
- 3From: Malaria Journal. (Vol. 11) Peer-ReviewedBackground Despite a significant reduction in the number of malaria cases in Guyana and Suriname, this disease remains a major problem in the interior of both countries, especially in areas with gold mining and logging...
- 4From: Malaria Journal. (Vol. 11) Peer-ReviewedBackground Nitidine is thought to be the main active ingredient in several traditional anti-malarial remedies used in different parts of the world. The widespread use of these therapies stresses the importance of...
- 5From: Malaria Journal. (Vol. 11) Peer-ReviewedBackground A prospective study aiming at assessing the effect of adding a third dose sulphadoxine-pyrimethamine (SP) to the standard two-dose intermittent preventive treatment for pregnant women was carried out in...
- 6From: Malaria Journal. (Vol. 11) Peer-ReviewedBackground Nigeria instituted intermittent preventive treatment for malaria (IPTp) using sulphadoxine-pyrimethamine (SP) for pregnant women in 2001, but coverage remains low. This study examined the influence of...
- 7From: Malaria Journal. (Vol. 11, Issue 1) Peer-Reviewed
A simple and inexpensive haemozoin-based colorimetric method to evaluate anti-malarial drug activity
Background The spread of drug resistance in malaria parasites and the limited number of effective drugs for treatment indicates the need for new anti-malarial compounds. Current assays evaluating drugs against... - 8From: Malaria Journal. (Vol. 11, Issue 1) Peer-ReviewedPregnant women are more susceptible to malaria than their non-pregnant counterparts. Less is known about the risk of malaria in the postpartum period. The epidemiology of postpartum malaria was systematically reviewed....
- 9From: Malaria Journal. (Vol. 11, Issue 1) Peer-ReviewedBackground Monitoring resistance phenotypes for Plasmodium falciparum, using in vitro growth assays, and relating findings to parasite genotype has proved particularly challenging for the study of resistance to...
- 10From: Malaria Journal. (Vol. 11, Issue 1) Peer-ReviewedBackground Serine hydroxymethyltransferase (SHMT), a pyridoxal phosphate-dependent enzyme, plays a vital role in the de novo pyrimidine biosynthesis pathway in malaria parasites. Two genes have been identified in...
- 11From: Malaria Journal. (Vol. 11, Issue 1) Peer-ReviewedBackground Malaria and HIV co-infection adversely impact the outcome of both diseases and previous studies have mostly focused on falciparum malaria. Plasmodium vivax contributes to almost half of the malaria cases...
- 12From: Malaria Journal. (Vol. 11, Issue 1) Peer-ReviewedParenteral artesunate has been shown to be a superior treatment option compared to parenteral quinine in adults and children with severe malaria. Little evidence, however, is available on long-term safety. Recently,...
- 13From: Malaria Journal. (Vol. 11) Peer-ReviewedBackground Drug resistance to anti-malarials is a major public health problem worldwide. This study aimed at establishing the efficacy of artemether-lumefantrine (ACT) in Igombe-Mwanza, north-western Tanzania after a...
- 14From: Malaria Journal. (Vol. 11) Peer-ReviewedBackground A major concern in malaria vaccine development is genetic polymorphisms typically observed among Plasmodium isolates in different geographical areas across the world. Highly polymorphic regions have been...
- 15From: Malaria Journal. (Vol. 11) Peer-ReviewedBackground Insecticide-treated nets (ITNs) are effective tools for malaria prevention and can significantly reduce severe disease and mortality due to malaria, especially among children under five in endemic areas....
- 16From: Malaria Journal. (Vol. 11, Issue 1) Peer-ReviewedBackground Microarray studies using in vitro cultures of synchronized, blood-stage Plasmodium falciparum malaria parasites have revealed a 'just-in-time' cascade of gene expression with some indication that these...
- 17From: Malaria Journal. (Vol. 11, Issue 1) Peer-ReviewedBackground The Malaria in Pregnancy (MiP) Library is a bibliographic database that was created by the MiP Consortium in 2005 and is updated every four months using a standardized search protocol. A bibliometric...
- 18From: Malaria Journal. (Vol. 11, Issue 1) Peer-ReviewedCountries in the Asia Pacific region are making substantial progress toward eliminating malaria, but their success stories are rarely heard by a global audience. "Malaria 2012: Saving Lives in the Asia-Pacific," a...
- 19From: Malaria Journal. (Vol. 11, Issue 1) Peer-ReviewedBackground The Lao Government changed the national policy for uncomplicated Plasmodium falciparum malaria from chloroquine to artemether-lumefantrine (AL) in 2005. Since then, no information on AL efficacy has been...
- 20From: Malaria Journal. (Vol. 11, Issue 1) Peer-ReviewedBackground The recommendation of artemisinin combination therapy (ACT) as first-line treatment for uncomplicated falciparum malaria is supported by a plethora of high quality clinical trials. However, their...