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- 1From: Microbial Cell Factories. (Vol. 11) Peer-ReviewedBackground Yeast strains endowed with robustness towards copper and/or enriched in intracellular Cu might find application in biotechnology processes, among others in the production of functional foods. Moreover,...
- 2From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground Recent successes in the determination of G-protein coupled receptor (GPCR) structures have relied on the ability of receptor variants to overcome difficulties in expression and purification. Therefore, the...
- 3From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground The Crabtree-negative yeast species Kluyveromyces lactis has been established as an attractive microbial expression system for recombinant proteins at industrial scale. Its LAC genes allow for utilization...
- 4From: Microbial Cell Factories. (Vol. 11) Peer-ReviewedBackground Although the occurrence, biosynthesis and possible functions of glycoproteins are increasingly documented for pathogens, glycoproteins are not yet widely described in probiotic bacteria. Nevertheless,...
- 5From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground Buffering to achieve pH control is crucial for successful trichloroethene (TCE) anaerobic bioremediation. Bicarbonate (HCO.sub.3.sup.-) is the natural buffer in groundwater and the buffer of choice in the...
- 6From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground The influence of carbon dioxide and oxygen on microbial secondary metabolite producers and the maintenance of these two parameters at optimal levels have been studied extensively. Nevertheless, most...
- 7From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground A useful goal for metabolic engineering would be to generate non-growing but metabolically active quiescent cells which would divert the metabolic fluxes towards product formation rather than growth....
- 8From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground The integration of biotechnology into chemical manufacturing has been recognized as a key technology to build a sustainable society. However, the practical applications of biocatalytic chemical conversions...
- 9From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground During bioprocess development, secondary screening is a key step at the boundary between laboratory and industrial conditions. To ensure an effective high-throughput screening, miniaturized laboratory...
- 10From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground Lipases (EC 3.1.1.3) catalyze the hydrolysis of triacyl glycerol to glycerol and are involved in the synthesis of both short chain and long chain acylglycerols. They are widely used industrially in various...
- 11From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground There has been renewed interest in biopharmaceuticals based on plasmid DNA (pDNA) in recent years due to the approval of several veterinary DNA vaccines, on-going clinical trials of human pDNA-based...
- 12From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground Purine nucleotides exhibit various functions in cellular metabolism. Besides serving as building blocks for nucleic acid synthesis, they participate in signaling pathways and energy metabolism. Further,...
- 13From: Microbial Cell Factories. (Vol. 11) Peer-ReviewedBackground Trichoderma reesei is the preferred organism for producing industrial cellulases. However, a more efficient heterologous expression system for enzymes from different organism is needed to further improve...
- 14From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedThe production of heterologous disulfide bonded proteins in bacteria remains a biotechnological challenge. A rapid literature survey results in the identification of some interesting proposals, such as the option of...
- 15From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground TliA is a thermostable lipase secreted by the type 1 secretion system (T1SS) of Pseudomonas fluorescens. The secretion is promoted by its secretion/chaperone domain located near the C-terminus, which is...
- 16From: Microbial Cell Factories. (Vol. 11) Peer-ReviewedBackground Little is known about the structure and regulation of fungal [alpha]-L-rhamnosidase genes despite increasing interest in the biotechnological potential of the enzymes that they encode. Whilst the...
- 17From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedBackground A bacterial strain previously isolated from pyrite mine drainage and named BAS-10 was tentatively identified as Klebsiella oxytoca. Unlikely other enterobacteria, BAS-10 is able to grow on Fe(III)-citrate...
- 18From: Microbial Cell Factories. (Vol. 11) Peer-ReviewedBackground Fermentation of xylose, the major component in hemicellulose, is essential for economic conversion of lignocellulosic biomass to fuels and chemicals. The yeast Scheffersomyces stipitis (formerly known as...
- 19From: Microbial Cell Factories. (Vol. 11) Peer-ReviewedBackground The Antarctic fungus Lecanicillium muscarium CCFEE 5003 is one of the most powerful chitinolytic organisms. It can produce high level of chitinolytic enzymes in a wide range of temperatures...
- 20From: Microbial Cell Factories. (Vol. 11, Issue 1) Peer-ReviewedOver the past decades, nitrilases have drawn considerable attention because of their application in nitrile degradation as prominent biocatalysts. Nitrilases are derived from bacteria, filamentous fungi, yeasts, and...