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- 1From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Recent evidence shows that allograft survival rates show a positive correlation with the number of circulating T regulatory cells (Tregs). This study investigated both the number and the cytokine profiles...
- 2From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Complement C2 deficiency is the most common genetically determined complete complement deficiency and is associated with a number of diseases. Most prominent are the associations with recurrent serious...
- 3From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Inappropriate responses to normal intestinal bacteria may be involved in the development of Inflammatory Bowel Diseases (IBD, e.g. Crohn's Disease (CD), Ulcerative Colitis (UC)) and variations in the host...
- 4From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground It is well established that adaptive immune responses induced by hypercholesterolemia play an important role in the development of atherosclerosis, but the pathways involved remain to be fully...
- 5From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground At present, the relatively sudden appearance and explosive spread of HIV throughout Africa and around the world beginning in the 1950s has never been adequately explained. Theorizing that this phenomenon...
- 6From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground The adenosine/uridine-rich element (ARE)-binding protein AUF1 functions to regulate the inflammatory response through the targeted degradation of cytokine and other mRNAs that contain specific AREs in...
- 7From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground The use of mouse models to study human disease provides useful data that can provide support for research projects or an existing drug discovery program. How well a model recapitulates the human condition...
- 8From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Yersinia pestis is the causative agent of pneumonic plague; recently, we and others reported that during the first 24-36 hours after pulmonary infection with Y. pestis pro-inflammatory cytokine expression...
- 9From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Iloprost has been suggested to possess anti-inflammatory and immunomodulating actions and it is widely use as a vasodilatator in systemic sclerosis (SSc). In this study we evaluate the effect of iloprost...
- 10From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Immunization with the spike protein (S) of severe acute respiratory syndrome (SARS)-coronavirus (CoV) in mice is known to produce neutralizing antibodies and to prevent the infection caused by SARS-CoV....
- 11From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Remission of multiple sclerosis during periods of high ovarian hormone secretion (such as pregnancy) has led to a great deal of interest in the potential for estrogens to treat autoimmune disease. Previous...
- 12From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Previous reports have shown that peptides derived from the apolipoprotein E receptor binding region and the amphipathic [alpha]-helical domains of apolipoprotein AI have broad anti-infective activity and...
- 13From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Human Papillomavirus, HPV, is the main etiological factor for cervical cancer. Different studies show that in women infected with HPV there is a positive correlation between lesion grade and number of...
- 14From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Ticks (Acari: Ixodidae) are vectors of pathogens worldwide that cause diseases in humans and animals. Ticks and pathogens have co-evolved molecular mechanisms that contribute to their mutual development...
- 15From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground The lymph node (LN) is a crossroads of blood and lymphatic vessels allowing circulating lymphocytes to efficiently recognize foreign molecules displayed on antigen presenting cells. Increasing evidence...
- 16From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Previous studies of T cell activation in dengue infection have focused on restriction of specific T cell receptors (TCRs) and classical MHC molecules. However, bystander T cell activation, which is TCR...
- 17From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Bifidobacteria and lactobacilli are among the early and important colonizers of the gastrointestinal tract and are generally considered to be part of a normal, healthy microbiota. It is believed that...
- 18From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Mast cells have recently gained new importance as immunoregulatory cells that are involved in numerous pathological processes. One result of these processes is an increase in mast cell numbers at...
- 19From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Chemokines, a group of small and structurally related proteins, mediate chemotaxis of various cell types via chemokine receptors. In mammals, seven different CXC chemokine receptors denoted as CXCR1 to...
- 20From: BMC Immunology. (Vol. 11) Peer-ReviewedBackground Several observations suggest that immunological events early after chemotherapy, possibly during the period of severe treatment-induced cytopenia, are important for antileukemic immune reactivity in acute...