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- 1From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedHeart failure (HF) is a leading cause of morbidity and mortality worldwide. Management of HF involves accurate diagnosis and implementation of evidence-based treatment strategies. Costs related to the care of patients...
- 2From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedOptimal therapeutic decision-making requires integration of patient-specific and therapy-specific information at the point of care, particularly when treating patients with complex cardiovascular conditions. The...
- 3From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedThe majority of patients who discontinue statin therapy owing to an adverse event are able to tolerate this medication if it is represcribed. This finding from a retrospective cohort study of patients treated at medical...
- 4From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedFindings from the DKCRUSH-III trial were presented at the 2013 ACC Scientific Sessions. At 1 year, culotte stenting was associated with more major adverse cardiac events than the double kissing crush strategy (16.3% vs...
- 5From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedDespite presenting early after symptom onset, some patients with ST-segment elevation myocardial infarction are unable to receive mechanical reperfusion within 60 min. The STREAM trial shows that, among these...
- 6From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedThe results of MASS COMM support the safety of performing percutaneous coronary intervention at centres without on-site cardiothoracic surgery services. To translate these findings into clinical practice, robust quality...
- 7From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedCigarette smokers no longer have the excuse that quitting smoking would be almost as bad for their cardiovascular health as continuing to smoke, because of the weight gain often associated with smoking cessation....
- 8From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedHIV infection is associated with increased risk of acute myocardial infarction (HR 1.48, 95% CI 1.27-1.72), even in patients achieving HIV-1 RNA levels <500 copies per ml (HR 1.39, 95% CI 1.17-1.66), according to a...
- 9From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedThe much-anticipated results of the international RESPECT and PC trials, first presented at TCT 2012, have now been published in the NEJM. In the primary analysis of each study, closure of patent foramen ovale (PFO)...
- 10From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedIn the Review article by Fyhrquist et al. (The roles of senescence and telomere shortening in cardiovascular disease. Nat. Rev. Cardiol. doi:10.1038/nrcardio.2013.30), (1) the authors extensively appraise the role in...
- 11From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedNew analysis of data from the randomized, controlled, DIG trial has indicated that digoxin might help to reduce the risk of 30-day all-cause hospital admission in ambulatory, elderly patients with heart failure and...
- 12From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedResults from the REVIVE trials, first presented at the 2005 AHA Scientific Sessions, have finally been published. REVIVE I was designed to develop a measure of efficacy for the treatment of patients with acutely...
- 13From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedThe primary goals of personalized medicine are to optimize diagnostic and treatment strategies by tailoring them to the specific characteristics of an individual patient. In this Review, we summarize basic concepts and...
- 14From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedCryoballoon ablation was developed to be a single-delivery technique for isolation of the pulmonary veins in patients with atrial fibrillation (AF). The STOP AF Cryoablation Investigators have published the results of...
- 15From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedA prospective, longitudinal study has indicated that late gadolinium enhancement CMR imaging for the assessment of midwall fibrosis might be useful in the risk stratification of patients with dilated cardiomyopathy. The...
- 16From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedCangrelor is an intravenous, reversibly binding, [P2Y.sub.12]-receptor inhibitor with a rapid onset of action that yields a high level of receptor inhibition within minutes. The CHAMPION PHOENIX study has demonstrated...
- 17From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedThree randomized clinical trials have added data to the debate about whether off-pump CABG surgery has any advantages over the on-pump approach. A growing consensus is emerging; however, understanding the conflicting...
- 18From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedHistorically, the USA and European countries have been the dominant figures in medical research. However, in the past 10 years, Asia has emerged as a new 'hot spot' for clinical research owing to the tremendous...
- 19From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedLess than 5% of patients who have experienced a cardiovascular event subsequently adopt three healthy lifestyle behaviours (smoking cessation, physical acitivy, healthy diet), according to data from the PURE study. This...
- 20From: Nature Reviews Cardiology. (Vol. 10, Issue 6) Peer-ReviewedAtrial fibrillation (AF) is the most-common sustained arrhythmia observed in clinical practice, but response to therapy is highly variable between patients. Current drug therapies to suppress AF are incompletely and...